Functional Interplay between Histone H2B ADP-Ribosylation and Phosphorylation Controls Adipogenesis.
Sign Up to like & getrecommendations! Published in 2020 at "Molecular cell"
DOI: 10.1016/j.molcel.2020.08.002
Abstract: Although ADP-ribosylation of histones by PARP-1 has been linked to genotoxic stress responses, its role in physiological processes and gene expression has remained elusive. We found that NAD+-dependent ADP-ribosylation of histone H2B-Glu35 by small nucleolar… read more here.
Keywords: adp ribosylation; histone h2b; functional interplay; h2b ... See more keywords
A functional interplay between intein and extein sequences in protein splicing compensates for the essential block B histidine† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c8sc01074a
Sign Up to like & getrecommendations! Published in 2019 at "Chemical Science"
DOI: 10.1039/c8sc01074a
Abstract: Steric bulk can compensate for a catalytically critical histidine in an intein's active site and promote the N–S acyl shift. read more here.
Keywords: interplay intein; histidine; extein sequences; functional interplay ... See more keywords
No-nonsense: insights into the functional interplay of nonsense-mediated mRNA decay factors
Sign Up to like & getrecommendations! Published in 2022 at "Biochemical Journal"
DOI: 10.1042/bcj20210556
Abstract: Nonsense-mediated messenger RNA decay (NMD) represents one of the main surveillance pathways used by eukaryotic cells to control the quality and abundance of mRNAs and to degrade viral RNA. NMD recognises mRNAs with a premature… read more here.
Keywords: nonsense; nonsense mediated; decay; mrna decay ... See more keywords
Functional interplay between Mediator and RNA polymerase II in Rad2/XPG loading to the chromatin
Sign Up to like & getrecommendations! Published in 2019 at "Nucleic Acids Research"
DOI: 10.1093/nar/gkz598
Abstract: Abstract Transcription and maintenance of genome integrity are fundamental cellular functions. Deregulation of transcription and defects in DNA repair lead to serious pathologies. The Mediator complex links RNA polymerase (Pol) II transcription and nucleotide excision… read more here.
Keywords: rad2; transcription; mediator; functional interplay ... See more keywords
A Functional Interplay between IGF-1 and Adiponectin
Sign Up to like & getrecommendations! Published in 2017 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms18102145
Abstract: A functional relationship is suggested between two well-known protein hormones, insulin-like growth factor 1 (IGF-1) and adiponectin. In the last two decades in fact, different experimental evidence has indicated a non-random link between them. Here,… read more here.
Keywords: igf; igf adiponectin; interplay igf; functional interplay ... See more keywords
Novel Insights into the Biochemical Mechanism of CK1ε and its Functional Interplay with DDX3X
Sign Up to like & getrecommendations! Published in 2020 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms21176449
Abstract: Casein Kinase 1 epsilon (CK1ε) is a member of the serine (Ser)/threonine (Thr) CK1 family, known to have crucial roles in several biological scenarios and, ever more frequently, in pathological contexts, such as cancer. Recently,… read more here.
Keywords: ck1; functional interplay; novel insights; casein ... See more keywords
Functional Interplay between Arginyl-tRNA Synthetases and Arginyltransferase
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms231710160
Abstract: Protein arginylation, mediated by arginyltransferase ATE1, is a posttranslational modification of emerging biological importance that consists of transfer of the amino acid Arg to protein and peptide substrates. ATE1 utilizes charged tRNAArg as the donor… read more here.
Keywords: arginyl trna; trna synthetases; arginylation; functional interplay ... See more keywords