Characterization of super‐enhancer‐associated functional lncRNAs acting as ceRNAs in ESCC
Sign Up to like & getrecommendations! Published in 2020 at "Molecular Oncology"
DOI: 10.1002/1878-0261.12726
Abstract: Long noncoding RNAs (lncRNAs) have important regulatory roles in cancer biology. Although some lncRNAs have well‐characterized functions, the vast majority of this class of molecules remains functionally uncharacterized. To systematically pinpoint functional lncRNAs, a computational… read more here.
Keywords: characterization super; lncrnas acting; acting cernas; escc ... See more keywords
Identify Functional lncRNAs in Nonalcoholic Fatty Liver Disease by Constructing a ceRNA Network
Sign Up to like & getrecommendations! Published in 2022 at "ACS Omega"
DOI: 10.1021/acsomega.2c01801
Abstract: Aim: To identify functional long noncoding RNAs (lncRNAs) by constructing a NAFLD-related lncRNA–miRNA–mRNA network (NLMMN) based on the hypothesis that lncRNAs, as competitive endogenous RNAs (ceRNAs), are able to regulate mRNA functions by competitive binding… read more here.
Keywords: hepg2 cells; identify functional; functional lncrnas; cerna network ... See more keywords
LncReader: identification of dual functional long noncoding RNAs using a multi-head self-attention mechanism
Sign Up to like & getrecommendations! Published in 2022 at "Briefings in bioinformatics"
DOI: 10.1093/bib/bbac579
Abstract: Long noncoding ribonucleic acids (RNAs; LncRNAs) endowed with both protein-coding and noncoding functions are referred to as 'dual functional lncRNAs'. Recently, dual functional lncRNAs have been intensively studied and identified as involved in various fundamental… read more here.
Keywords: head self; self attention; functional lncrnas; multi head ... See more keywords
LncFunNet: an integrated computational framework for identification of functional long noncoding RNAs in mouse skeletal muscle cells
Sign Up to like & getrecommendations! Published in 2017 at "Nucleic Acids Research"
DOI: 10.1093/nar/gkx232
Abstract: Abstract Long noncoding RNAs (lncRNAs) are key regulators of diverse cellular processes. Recent advances in high-throughput sequencing have allowed for an unprecedented discovery of novel lncRNAs. To identify functional lncRNAs from thousands of candidates for… read more here.
Keywords: lncfunnet; long noncoding; computational framework; noncoding rnas ... See more keywords