Time to Functional Loss as an Endpoint in Huntington's Disease Trials: Enrichment and Sample Size
Sign Up to like & getrecommendations! Published in 2024 at "Movement Disorders"
DOI: 10.1002/mds.29963
Abstract: Clinical trial scenarios can be modeled using data from observational studies, providing critical information for design of real‐world trials. The Huntington's Disease Integrated Staging System (HD‐ISS) characterizes disease progression over an individual's lifespan and allows… read more here.
Keywords: disease; loss endpoint; huntington disease; functional loss ... See more keywords
Xenon-enhanced CT using subtraction CT: Basic and preliminary clinical studies for comparison of its efficacy with that of dual-energy CT and ventilation SPECT/CT to assess regional ventilation and pulmonary functional loss in smokers.
Sign Up to like & getrecommendations! Published in 2017 at "European journal of radiology"
DOI: 10.1016/j.ejrad.2016.10.035
Abstract: PURPOSE To prospectively and directly compare the capability for assessments of regional ventilation and pulmonary functional loss in smokers of xenon-ventilation CT obtained with the dual-energy CT (DE-CT) and subtraction CT (Sub-CT) MATERIALS AND METHODS:… read more here.
Keywords: functional loss; xenon enhanced; ventilation; regional ventilation ... See more keywords
Monitoring Glaucomatous Functional Loss Using an Artificial Intelligence-Enabled Dashboard.
Sign Up to like & getrecommendations! Published in 2020 at "Ophthalmology"
DOI: 10.1016/j.ophtha.2020.03.008
Abstract: PURPOSE To develop an artificial intelligence (AI) dashboard for monitoring glaucomatous functional loss. DESIGN Retrospective, cross-sectional, longitudinal cohort study. PARTICIPANTS Of 31 591 visual fields (VFs) on 8077 subjects, 13 231 VFs from the most recent visit… read more here.
Keywords: functional loss; glaucomatous functional; monitoring glaucomatous; artificial intelligence ... See more keywords
Onco-functional outcome after resection for eloquent glioblastoma (GLIOFO): A propensity-score matched analysis of an international, multicentre, cohort study.
Sign Up to like & getrecommendations! Published in 2024 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2024.42.16_suppl.e14017
Abstract: e14017 Background: Minimizing residual volume and preventing functional loss are the main goals in glioblastoma resections in eloquent areas. However, their combined impact on patient outcomes remains poorly understood. We therefore developed a novel onco-functional… read more here.
Keywords: cohort; resection; propensity score; functional loss ... See more keywords
A Transcriptomic Analysis of Tobacco Leaf with the Functional Loss of the Plastid rpoB Operon Caused by TALEN-Mediated Double-Strand Breakage
Sign Up to like & getrecommendations! Published in 2022 at "Plants"
DOI: 10.3390/plants11212860
Abstract: At least two sets of RNA polymerase (RNAP), nucleus (NEP)- and plastid (PEP)-encoded polymerases, recognizing distinct promoters exist in the plastids of land plants. Most plastid genes are regulated by multiple promoters with different strengths… read more here.
Keywords: functional loss; tobacco; gene expression; double strand ... See more keywords