Articles with "functional mechanistic" as a keyword



Photo by bermixstudio from unsplash

Abstract 1349: Functional and mechanistic characterization of PRMT6 regulated autophagy in hepatocellular carcinoma

Sign Up to like & get
recommendations!
Published in 2018 at "Cancer Research"

DOI: 10.1158/1538-7445.am2018-1349

Abstract: Hepatocellular carcinoma (HCC) is a major health burden worldwide. Tumor recurrence and therapy resistance represent major obstacles in the treatment of the disease, with their mechanism of action largely uncharacterized. Autophagy is a critical survival… read more here.

Keywords: hepatocellular carcinoma; prmt6; hcc; functional mechanistic ... See more keywords
Photo from wikipedia

Structural, Functional and Mechanistic Insights Uncover the Fundamental Role of Orphan Connexin62 in Platelets.

Sign Up to like & get
recommendations!
Published in 2020 at "Blood"

DOI: 10.1182/blood.2019004575

Abstract: Connexins (Cxs) oligomerise to form hexameric hemichannels in the plasma membrane that can further dock together on adjacent cells to form gap junctions and facilitate intercellular-trafficking of molecules. In this study, we report the expression… read more here.

Keywords: fundamental role; functional mechanistic; structural functional; function ... See more keywords