The circulating microbiome signature and inferred functional metagenomics in alcoholic hepatitis
Sign Up to like & getrecommendations! Published in 2018 at "Hepatology"
DOI: 10.1002/hep.29623
Abstract: Intestinal dysbiosis is implicated in alcoholic hepatitis (AH). However, changes in the circulating microbiome, its association with the presence and severity of AH, and its functional relevance in AH is unknown. Qualitative and quantitative assessment… read more here.
Keywords: changes circulating; functional metagenomics; alcoholic hepatitis; hepatology ... See more keywords
Functional metagenomics identifies novel genes ABCTPP, TMSRP1 and TLSRP1 among human gut enterotypes
Sign Up to like & getrecommendations! Published in 2018 at "Scientific Reports"
DOI: 10.1038/s41598-018-19862-5
Abstract: Every niche in the biosphere is touched by the seemingly endless capacity of microbes to transform the world around them by adapting swiftly and flexibly to the environmental changes, likewise the gastrointestinal tract is no… read more here.
Keywords: gut; human gut; identifies novel; functional metagenomics ... See more keywords
Structure Elucidation and Biochemical Characterization of Environmentally Relevant Novel Extradiol Dioxygenases Discovered by a Functional Metagenomics Approach
Sign Up to like & getrecommendations! Published in 2019 at "mSystems"
DOI: 10.1128/msystems.00316-19
Abstract: The disposal and degradation of xenobiotic compounds have been serious issues due to their recalcitrant properties. Microbial oxygenases are the fundamental enzymes involved in biodegradation that oxidize the substrate by transferring oxygen from molecular oxygen.… read more here.
Keywords: catechol; catechol dioxygenases; structure; functional metagenomics ... See more keywords
Isolation of novel cold-tolerance genes from rhizosphere microorganisms of Antarctic plants by functional metagenomics
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2022.1026463
Abstract: The microorganisms that thrive in Antarctica, one of the coldest environments on the planet, have developed diverse adaptation mechanisms to survive in these extreme conditions. Through functional metagenomics, in this work, 29 new genes related… read more here.
Keywords: tolerance genes; tolerance; isolation novel; antarctic plants ... See more keywords
Discovery of novel carbohydrate degrading enzymes from soda lakes through functional metagenomics
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2022.1059061
Abstract: Extremophiles provide a one-of-a-kind source of enzymes with properties that allow them to endure the rigorous industrial conversion of lignocellulose biomass into fermentable sugars. However, the fact that most of these organisms fail to grow… read more here.
Keywords: carbohydrate degrading; degrading enzymes; soda lakes; lignocellulose biomass ... See more keywords
Functional metagenomics uncovers nitrile-hydrolysing enzymes in a coal metagenome
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Molecular Biosciences"
DOI: 10.3389/fmolb.2023.1123902
Abstract: Introduction: Nitriles are the most toxic compounds that can lead to serious human illness through inhalation and consumption due to environmental pollution. Nitrilases can highly degrade nitriles isolated from the natural ecosystem. In the current… read more here.
Keywords: nitrile hydrolysing; nitrilase; coal metagenome; metagenomics uncovers ... See more keywords
Novel Soil-Derived Beta-Lactam, Chloramphenicol, Fosfomycin and Trimethoprim Resistance Genes Revealed by Functional Metagenomics
Sign Up to like & getrecommendations! Published in 2021 at "Antibiotics"
DOI: 10.3390/antibiotics10040378
Abstract: Antibiotic resistance genes (ARGs) in soil are considered to represent one of the largest environmental resistomes on our planet. As these genes can potentially be disseminated among microorganisms via horizontal gene transfer (HGT) and in… read more here.
Keywords: trimethoprim resistance; resistance; functional metagenomics; soil ... See more keywords