Adenylyl cyclase isoform 1 contributes to sinoatrial node automaticity via functional microdomains
Sign Up to like & getrecommendations! Published in 2022 at "JCI Insight"
DOI: 10.1172/jci.insight.162602
Abstract: Sinoatrial node (SAN) cells are the heart’s primary pacemaker. Their activity is tightly regulated by β-adrenergic receptor (β-AR) signaling. Adenylyl cyclase (AC) is a key enzyme in the β-AR pathway that catalyzes the production of… read more here.
Keywords: sinoatrial node; functional microdomains; isoform; adenylyl cyclase ... See more keywords