Accelerating Discovery of Functional Mutant Alleles in Cancer.
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DOI: 10.1158/2159-8290.cd-17-0321
Abstract: Most mutations in cancer are rare, which complicates the identification of therapeutically significant mutations and thus limits the clinical impact of genomic profiling in patients with cancer. Here, we analyzed 24,592 cancers including 10,336 prospectively… read more here.
Keywords: mutant alleles; accelerating discovery; discovery functional; functional mutant ... See more keywords