Synergistic Functional Nanomedicine Enhances Ferroptosis Therapy for Breast Tumors by a Blocking Defensive Redox System.
Sign Up to like & getrecommendations! Published in 2023 at "ACS applied materials & interfaces"
DOI: 10.1021/acsami.2c19585
Abstract: The upregulation of dihydroorotate dehydrogenase (DHODH) redox systems inside tumor cells provides a powerful shelter against lipid peroxidation (LPO), impeding ferroptosis-induced antitumor responses. To solve this issue, we report a strategy to block redox systems… read more here.
Keywords: ferroptosis therapy; redox; synergistic functional; ferroptosis ... See more keywords
Designer Functional Nanomedicine for Myocardial Repair by Regulating the Inflammatory Microenvironment
Sign Up to like & getrecommendations! Published in 2022 at "Pharmaceutics"
DOI: 10.3390/pharmaceutics14040758
Abstract: Acute myocardial infarction is a major global health problem, and the repair of damaged myocardium is still a major challenge. Myocardial injury triggers an inflammatory response: immune cells infiltrate into the myocardium while activating myofibroblasts… read more here.
Keywords: myocardial injury; inflammatory microenvironment; designer functional; functional nanomedicine ... See more keywords