Recent advances of functional nucleic acid-based sensors for point-of-care detection of SARS-CoV-2
Sign Up to like & getrecommendations! Published in 2022 at "Mikrochimica Acta"
DOI: 10.1007/s00604-022-05242-4
Abstract: This review focuses on critical scientific barriers that the field of point-of-care (POC) testing of SARS-CoV-2 is facing and possible solutions to overcome these barriers using functional nucleic acid (FNA)-based technology. Beyond the summary of… read more here.
Keywords: sars cov; point care; based sensors; functional nucleic ... See more keywords
Photocaged functional nucleic acids for spatiotemporal imaging in biology.
Sign Up to like & getrecommendations! Published in 2020 at "Current opinion in chemical biology"
DOI: 10.1016/j.cbpa.2020.05.003
Abstract: Imaging of species in living organisms with high spatiotemporal resolution is essential for understanding biological processes. While functional nucleic acids (FNAs), such as catalytic nucleic acids and aptamers, have emerged as effective sensors for a… read more here.
Keywords: nucleic acids; acids spatiotemporal; functional nucleic; photocaged functional ... See more keywords
Recent advances on functional nucleic acid-based biosensors for detection of food contaminants.
Sign Up to like & getrecommendations! Published in 2021 at "Talanta"
DOI: 10.1016/j.talanta.2020.121565
Abstract: It has seen increasing development of reliable, robust, and flexible biosensors for rapid food-safety analysis in the past few decades. Recently, functional nucleic acid-based biosensors have attracted attention because of their programmability, bottom-up characteristics, and… read more here.
Keywords: nucleic acid; acid based; functional nucleic; based biosensors ... See more keywords
Panoply of Fluorescence Polarization/Anisotropy Signaling Mechanisms for Functional Nucleic Acid-Based Sensing Platforms.
Sign Up to like & getrecommendations! Published in 2018 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.7b04593
Abstract: Fluorescence polarization/anisotropy is a very popular technique that is widely used in homogeneous-phase immunoassays for the small molecule quantification. In the present Feature, we discuss how the potential of this signaling approach considerably expanded during… read more here.
Keywords: nucleic acid; functional nucleic; fluorescence polarization; polarization anisotropy ... See more keywords
Functional nucleic acid biosensors utilizing rolling circle amplification.
Sign Up to like & getrecommendations! Published in 2022 at "Chemical Society reviews"
DOI: 10.1039/d2cs00613h
Abstract: Functional nucleic acids (FNAs), including DNA aptamers and DNAzymes, are finding increasing use as molecular recognition elements for point-of-care (POC) assays and sensors. An ongoing challenge in the development of FNA-based POC sensors is the… read more here.
Keywords: rolling circle; circle amplification; biosensors utilizing; amplification ... See more keywords
Combating small molecule environmental contaminants: detection and sequestration using functional nucleic acids
Sign Up to like & getrecommendations! Published in 2022 at "Chemical Science"
DOI: 10.1039/d2sc00117a
Abstract: Small molecule contaminants pose a significant threat to the environment and human health. While regulations are in place for allowed limits in many countries, detection and remediation of contaminants in more resource-limited settings and everyday… read more here.
Keywords: small molecule; molecule; functional nucleic; combating small ... See more keywords
A versatile strategy for convenient circular bivalent functional nucleic acids construction
Sign Up to like & getrecommendations! Published in 2022 at "National Science Review"
DOI: 10.1093/nsr/nwac107
Abstract: ABSTRACT Functional nucleic acids (FNAs), such as aptamers, nucleic acid enzymes and riboswitches play essential roles in various fields of life sciences. Tailoring of ingenious chemical moieties toward FNAs can enhance their biomedical properties and/or… read more here.
Keywords: circular bivalent; functional nucleic; nucleic acids; versatile strategy ... See more keywords
Functional Nucleic Acid-Based Live-Cell Fluorescence Imaging
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Chemistry"
DOI: 10.3389/fchem.2020.598013
Abstract: Cell is the structural and functional unit of organism. It serves as a key research object in various biological processes, such as growth, ontogeny, metabolism and stress. Studying the spatiotemporal distribution and functional activity of… read more here.
Keywords: live cell; fluorescence imaging; functional nucleic; cell fluorescence ... See more keywords
Recent Progress in Functional-Nucleic-Acid-Based Fluorescent Fiber-Optic Evanescent Wave Biosensors
Sign Up to like & getrecommendations! Published in 2023 at "Biosensors"
DOI: 10.3390/bios13040425
Abstract: Biosensors capable of onsite and continuous detection of environmental and food pollutants and biomarkers are highly desired, but only a few sensing platforms meet the “2-SAR” requirements (sensitivity, specificity, affordability, automation, rapidity, and reusability). A… read more here.
Keywords: evanescent wave; fiber optic; fiber; optic evanescent ... See more keywords