Functional Phosphoproteomics in Cancer Chemoresistance Using CRISPR‐Mediated Base Editors
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DOI: 10.1002/advs.202200717
Abstract: Selective inhibition of targeted protein kinases is an effective therapeutic approach for treatment of human malignancies, which interferes phosphorylation of cellular substrates. However, a drug‐imposed selection creates pressures for tumor cells to acquire chemoresistance‐conferring mutations… read more here.
Keywords: crispr mediated; functional phosphoproteomics; phosphorylation; chemoresistance ... See more keywords