Designed helical peptides as functional probes for γ-secretase.
Sign Up to like & getrecommendations! Published in 2019 at "Biochemistry"
DOI: 10.1021/acs.biochem.9b00639
Abstract: γ-Secretase is a membrane-embedded aspartyl protease complex with presenilin as the catalytic component that cleaves within the transmembrane domain (TMD) of >90 known substrates, including the amyloid precursor protein (APP) of Alzheimer's disease. Processing by… read more here.
Keywords: helical peptides; functional probes; app; probes secretase ... See more keywords
Functional probes for cardiovascular molecular imaging.
Sign Up to like & getrecommendations! Published in 2018 at "Quantitative imaging in medicine and surgery"
DOI: 10.21037/qims.2018.09.19
Abstract: Cardiovascular diseases (CVDs) are a severely threatening disorder and frequently cause death in industrialized countries, posing critical challenges to modern research and medicine. Molecular imaging has been heralded as the solution to many problems encountered… read more here.
Keywords: medicine; functional probes; cardiovascular molecular; probes cardiovascular ... See more keywords