The functional relevance of shrimp C-type lectins in host-pathogen interactions.
Sign Up to like & getrecommendations! Published in 2020 at "Developmental and comparative immunology"
DOI: 10.1016/j.dci.2020.103708
Abstract: C-type lectins (CTLs) are key recognition proteins in shrimp immunity. A few years ago we reviewed sequence information, ligand specificity, expression profiles and specific functions of the shrimp CTLs. Since then, multiple integrated studies that… read more here.
Keywords: functional relevance; host pathogen; type lectins; pathogen interactions ... See more keywords
Functional relevance of miRNAs in premature ageing
Sign Up to like & getrecommendations! Published in 2017 at "Mechanisms of Ageing and Development"
DOI: 10.1016/j.mad.2017.05.003
Abstract: Ageing is a complex biological process characterized by the progressive loss of biological fitness due to the accumulation of macromolecular and cellular damage that affects most living organisms. Moreover, ageing is an important risk factor… read more here.
Keywords: functional relevance; relevance mirnas; mirnas premature; biology ... See more keywords
The functional relevance of dorsal motor systems for processing tool nouns– evidence from patients with focal lesions
Sign Up to like & getrecommendations! Published in 2020 at "Neuropsychologia"
DOI: 10.1016/j.neuropsychologia.2020.107384
Abstract: This study asks whether lesions in different parts of the brain have different effects on the processing of words typically used to refer to objects with and without action affordances, for example tools and animal… read more here.
Keywords: focal lesions; functional relevance; patients focal; dorsal motor ... See more keywords
Applying a Conservation-Based Approach for Predicting Novel Phosphorylation Sites in Eukaryotes and Evaluating Their Functional Relevance
Sign Up to like & getrecommendations! Published in 2025 at "Journal of Proteome Research"
DOI: 10.1021/acs.jproteome.5c00278
Abstract: Protein phosphorylation, a key post-translational modification, is central to cellular signalling and disease pathogenesis. The development of high-throughput proteomics pipelines has led to the discovery of large numbers of phosphorylated protein motifs and sites (phosphosites)… read more here.
Keywords: phosphorylation; conservation; functional relevance; protein ... See more keywords
Non-epigenetic induction of HEXIM1 by DNMT1 inhibitors and functional relevance
Sign Up to like & getrecommendations! Published in 2020 at "Scientific Reports"
DOI: 10.1038/s41598-020-78058-y
Abstract: We have been studying the role of Hexamethylene bisacetamide (HMBA) Induced Protein 1 (HEXIM1) as a tumor suppressor whose expression is decreased in breast and prostate cancer. The anti-cancer actions of HEXIM1 in melanomas and… read more here.
Keywords: functional relevance; hexim1; azadc induced; expression ... See more keywords
Functional relevance of computational fluid dynamics in the field of nasal obstruction: A literature review
Sign Up to like & getrecommendations! Published in 2019 at "Clinical Otolaryngology"
DOI: 10.1111/coa.13396
Abstract: Nasal airway obstruction (nasal obstruction) is a common symptom affecting the quality of life of patients. It can be estimated by patient perception or physical measurements. Computational fluid dynamics (CFD) can be used to analyse… read more here.
Keywords: nasal obstruction; functional relevance; obstruction; fluid dynamics ... See more keywords
Feasibility, efficacy, and functional relevance of automated auditory closed-loop suppression of slow-wave sleep in humans.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of sleep research"
DOI: 10.1111/jsr.13846
Abstract: Slow-wave sleep (SWS) is a fundamental physiological process, and its modulation is of interest for basic science and clinical applications. However, automatised protocols for the suppression of SWS are lacking. We describe the development of… read more here.
Keywords: functional relevance; slow wave; suppression; sws ... See more keywords
HERCing: Structural and Functional Relevance of the Large HERC Ubiquitin Ligases
Sign Up to like & getrecommendations! Published in 2019 at "Frontiers in Physiology"
DOI: 10.3389/fphys.2019.01014
Abstract: Homologous to the E6AP carboxyl terminus (HECT) and regulator of chromosome condensation 1 (RCC1)-like domain-containing proteins (HERCs) belong to the superfamily of ubiquitin ligases. HERC proteins are divided into two subfamilies, Large and Small HERCs.… read more here.
Keywords: functional relevance; hercing structural; large herc; ubiquitin ligases ... See more keywords
Functional relevance as a principle of translation problem-solving
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Psychology"
DOI: 10.3389/fpsyg.2022.1073532
Abstract: Translation is both an interpretive use of language and problem-solving activity. In his work, Ernst-August Gutt adopts a Relevance-Theoretic approach to unveil the inferential nature of translation as interpretive language use. He holds that in… read more here.
Keywords: relevance principle; problem solving; functional relevance; translation ... See more keywords
Zebrafish: A Powerful Model for Understanding the Functional Relevance of Noncoding Region Mutations in Human Genetic Diseases
Sign Up to like & getrecommendations! Published in 2019 at "Biomedicines"
DOI: 10.3390/biomedicines7030071
Abstract: Determining aetiology of genetic disorders caused by damaging mutations in protein-coding genes is well established. However, understanding how mutations in the vast stretches of the noncoding genome contribute to genetic abnormalities remains a huge challenge.… read more here.
Keywords: relevance noncoding; functional relevance; powerful model; zebrafish powerful ... See more keywords