Drug target prediction through deep learning functional representation of gene signatures
Sign Up to like & getrecommendations! Published in 2024 at "Nature Communications"
DOI: 10.1038/s41467-024-46089-y
Abstract: Many machine learning applications in bioinformatics currently rely on matching gene identities when analyzing input gene signatures and fail to take advantage of preexisting knowledge about gene functions. To further enable comparative analysis of OMICS… read more here.
Keywords: deep learning; functional representation; target; representation gene ... See more keywords
Functional representation of trigeminal nociceptive input in the human periaqueductal gray
Sign Up to like & getrecommendations! Published in 2024 at "Science Advances"
DOI: 10.1126/sciadv.adj8213
Abstract: The periaqueductal gray (PAG) is located in the mesencephalon in the upper brainstem and, as part of the descending pain modulation, is considered a crucial structure for pain control. Its modulatory effect on painful sensation… read more here.
Keywords: nociceptive input; pag; functional representation; periaqueductal gray ... See more keywords