Articles with "functional roles" as a keyword



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The Molecular Regulation and Functional Roles of NOX5.

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Published in 2019 at "Methods in molecular biology"

DOI: 10.1007/978-1-4939-9424-3_22

Abstract: NOX (NADPH oxidases) are a family of NADPH-dependent transmembrane enzymes that synthesize superoxide and other reactive oxygen species. There are seven isoforms (NOX1-5 and DUOX1-2) which derive from a common ancestral NOX. NOX enzymes are… read more here.

Keywords: molecular regulation; roles nox5; physiology; regulation functional ... See more keywords
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Functional roles of fucosylated and O-glycosylated cadherins during carcinogenesis and metastasis.

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Published in 2019 at "Cellular signalling"

DOI: 10.1016/j.cellsig.2019.109365

Abstract: Reduced cellular adhesiveness as a result of cadherin dysfunction is a defining feature of cancer and the mechanism involved in many aspects. Glycosylation is one of the most important post-translational modifications to cadherin. Major changes… read more here.

Keywords: roles fucosylated; fucosylated glycosylated; functional roles; glycosylated cadherins ... See more keywords
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Characterization of the soybean R2R3-MYB transcription factor GmMYB81 and its functional roles under abiotic stresses.

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Published in 2020 at "Gene"

DOI: 10.1016/j.gene.2020.144803

Abstract: R2R3-type MYBs are a key group of regulatory factors that control diverse developmental processes and stress tolerance in plants. Soybean is a major legume crop with the richness of seed protein and edible vegetable oil,… read more here.

Keywords: seed; gmmyb81; r2r3; abiotic stresses ... See more keywords
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The functional roles of the non-coding RNAs in molluscs.

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Published in 2020 at "Gene"

DOI: 10.1016/j.gene.2020.145300

Abstract: This review focus on the current knowledge of non-coding RNAs (ncRNAs) in molluscs. In this review, we provide an overview of long ncRNAs (lncRNA), microRNAs (miRNA) and piwi-interacting RNAs (piRNA), followed by evidence for the… read more here.

Keywords: coding rnas; rnas molluscs; non coding; functional roles ... See more keywords
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Structural and functional roles of 2'-O-ribose methylations and their enzymatic machinery across multiple classes of RNAs.

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Published in 2020 at "Current opinion in structural biology"

DOI: 10.1016/j.sbi.2020.05.008

Abstract: RNA complexity is augmented by numerous post-transcriptional modifications, which influence RNA function by modulating its structure and interactome. One prominent modification is methylation at the ribose 2'-hydroxyl group. 2'-O-methylation has been found in all RNA… read more here.

Keywords: methylation; machinery; enzymatic machinery; roles ribose ... See more keywords
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C-Terminal Domains of Spider Silk Proteins Having Divergent Structures but Conserved Functional Roles.

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Published in 2022 at "Biomacromolecules"

DOI: 10.1021/acs.biomac.1c01513

Abstract: Spider silk is self-assembled from silk proteins or spidroins. C-terminal domains (CTDs) of various types of spidroins are relatively conserved in amino acid sequences and are suggested to adopt similar structures and perform similar functional… read more here.

Keywords: terminal domains; spider silk; silk proteins; silk ... See more keywords
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The β and γ subunits play distinct functional roles in the α2βγ heterotetramer of human NAD-dependent isocitrate dehydrogenase

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Published in 2017 at "Scientific Reports"

DOI: 10.1038/srep41882

Abstract: Human NAD-dependent isocitrate dehydrogenase existing as the α2βγ heterotetramer, catalyzes the decarboxylation of isocitrate into α-ketoglutarate in the Krebs cycle, and is allosterically regulated by citrate, ADP and ATP. To explore the functional roles of… read more here.

Keywords: dependent isocitrate; human nad; nad dependent; isocitrate dehydrogenase ... See more keywords
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Functional roles of coral reef primary producers examined with stable isotopes

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Published in 2023 at "Marine and Freshwater Research"

DOI: 10.1071/mf22103

Abstract: Context Primary production on coral reefs varies under changing conditions such as light and nutrient availability. This variation causes changes in basal stable isotopes as photosynthetic and nutrient pathways change. Aims This study provides a… read more here.

Keywords: stable isotope; density; roles coral; primary producers ... See more keywords
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Functional roles for AGPAT6 in milk fat synthesis of buffalo mammary epithelial cells.

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Published in 2022 at "Animal biotechnology"

DOI: 10.1080/10495398.2022.2077738

Abstract: AGPAT6 plays a crucial role in the triglyceride (TG) synthesis pathway in mammals. However, its roles in buffalo lactation remain unknown. Therefore, we investigated the functional roles of AGPAT6 in milk fat synthesis by transfecting… read more here.

Keywords: roles agpat6; milk fat; synthesis; functional roles ... See more keywords
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Elucidating the functional roles of prokaryotic proteins using big data and artificial intelligence

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Published in 2023 at "FEMS Microbiology Reviews"

DOI: 10.1093/femsre/fuad003

Abstract: Abstract Annotating protein sequences according to their biological functions is one of the key steps in understanding microbial diversity, metabolic potentials, and evolutionary histories. However, even in the best-studied prokaryotic genomes, not all proteins can… read more here.

Keywords: big data; artificial intelligence; functional roles; elucidating functional ... See more keywords
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The multi-functional roles of the cGAS–STING signaling pathway in health and diseases

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Published in 2022 at "Journal of Molecular Cell Biology"

DOI: 10.1093/jmcb/mjac057

Abstract: T he innate immune system provides an important first line of defense against invading pathogens or harmful damages. Over the past decade, our understanding on the recognition of pathogenic nucleic acids by innate immunity has… read more here.

Keywords: signaling pathway; roles cgas; multi functional; sting signaling ... See more keywords