Chemoproteomics Reveals FAM114A2 as a Functional Target of Wikstroelide E for Reversal of HIV-1 Latency.
Sign Up to like & getrecommendations! Published in 2025 at "Journal of proteome research"
DOI: 10.1021/acs.jproteome.5c00242
Abstract: The latent reservoir of HIV-1 is a hidden fortress for escaping from the immune system and preventing antiretroviral therapy. The reversal of latent reservoirs is one of the key components of the HIV eradication strategy.… read more here.
Keywords: latency; hiv latency; functional target; reversal ... See more keywords
Chemical proteomics reveal CD147 as a functional target of pseudolaric acid B in human cancer cells.
Sign Up to like & getrecommendations! Published in 2017 at "Chemical communications"
DOI: 10.1039/c7cc04345g
Abstract: CD147 is a glycosylated transmembrane protein highly expressed on the surface of various tumor cells which plays vital roles in tumor invasion, progression and metastasis. We report the discovery of the natural product pseudolaric acid… read more here.
Keywords: reveal cd147; pseudolaric acid; functional target; chemical proteomics ... See more keywords