Dual Functionalization of Alkynes Utilizing the Redox Characteristics of Transition Metal Catalysts
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DOI: 10.1002/cctc.202100838
Abstract: Tri‐ and tetrasubstituted alkene scaffolds are prominent building blocks in many bioactive natural products, drug molecules, and key intermediates in various synthetic transformations. The dual functionalization of alkynes promises an easy introduction of functional groups… read more here.
Keywords: dual functionalization; functionalization alkynes; transition metal;
Recent advances in metal catalyzed or mediated cyclization/functionalization of alkynes to construct isoxazoles
Sign Up to like & getrecommendations! Published in 2020 at "Organic chemistry frontiers"
DOI: 10.1039/d0qo00609b
Abstract: Isoxazoles and their derivatives represent privileged heteroaromatic motifs, which exhibit remarkable biological and pharmaceutical activities. Notably, metal catalyzed or mediated cyclization/functionalization of alkynes such as alkynone oxime ethers, acetylinic oximes, propargylic amino ethers, alkynyl nitrile… read more here.
Keywords: catalyzed mediated; mediated cyclization; cyclization functionalization; functionalization alkynes ... See more keywords