Silicon-Tethered Strategies for C-H Functionalization Reactions.
Sign Up to like & getrecommendations! Published in 2017 at "Accounts of chemical research"
DOI: 10.1021/acs.accounts.7b00306
Abstract: Selective and efficient functionalization of ubiquitous C-H bonds is the Holy Grail of organic synthesis. Most advances in this area rely on employment of strongly or weakly coordinating directing groups (DGs) which have proven effective… read more here.
Keywords: easily installable; silicon; functionalization; employment ... See more keywords
Rieske Oxygenase Catalyzed C–H Bond Functionalization Reactions in Chlorophyll b Biosynthesis
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DOI: 10.1021/acscentsci.2c00058
Abstract: Rieske oxygenases perform precise C–H bond functionalization reactions in anabolic and catabolic pathways. These reactions are typically characterized as monooxygenation or dioxygenation reactions, but other divergent reactions are also catalyzed by Rieske oxygenases. Chlorophyll(ide) a… read more here.
Keywords: rieske; bond functionalization; cao; rieske oxygenase ... See more keywords
Synthesis of Atropisomers by Transition-Metal-Catalyzed Asymmetric C-H Functionalization Reactions.
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DOI: 10.1021/jacs.1c07635
Abstract: Transition-metal-catalyzed enantioselective C-H functionalization has become a powerful strategy for the formation of C-C or C-X bonds, enabling the highly asymmetric synthesis of a wide range of enantioenriched compounds. Atropisomers are widely found in natural… read more here.
Keywords: synthesis atropisomers; transition metal; metal catalyzed; functionalization ... See more keywords
Mechanistically Guided Workflow for Relating Complex Reactive Site Topologies to Catalyst Performance in C-H Functionalization Reactions.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.1c12198
Abstract: Leveraging congested catalyst scaffolds has emerged as a key strategy for altering innate substrate site-selectivity profiles in C-H functionalization reactions. Similar to enzyme active sites, optimal small molecule catalysts often feature reactive cavities tailored for… read more here.
Keywords: reactive site; site selectivity; complex reactive; functionalization ... See more keywords