One-pot Multicomponent Synthesis of Highly Functionalized 1,4-Dihydropyridines Using Porcine Pancreatic Lipase
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DOI: 10.1007/s40242-019-8277-4
Abstract: A series of highly functionalized 1,4-dihydropyridines was synthesized via one-pot multicomponent reactions of aromatic aldehyde, malononitrile and N-methyl-1-(methylthio)-2-nitroethenamine using Porcine pancreatic lipase(PPL) as catalyst in DMSO. This protocol is featured by mild reaction conditions, simple… read more here.
Keywords: porcine pancreatic; highly functionalized; pot multicomponent; using porcine ... See more keywords
Synthesis of functionalized 1,4-dihydropyridines containing benzosultams catalyzed by lipase
Sign Up to like & getrecommendations! Published in 2023 at "New Journal of Chemistry"
DOI: 10.1039/d2nj06028k
Abstract: As a base structural unit, 1,4-dihydropyridines (DHPs) containing benzosultams widely exist in bioactive molecules and drugs. These compounds are generally synthesized by organic-base catalyzed methods that require specifically functionalized substrates... read more here.
Keywords: catalyzed lipase; synthesis functionalized; benzosultams catalyzed; dihydropyridines containing ... See more keywords