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   Articles with "functionalized fused" as a keyword



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Lewis acid-catalyzed cyclodimerization of 1-substituted-3-arylvinylindoles leading to highly functionalized fused cyclopenta[b]indoles

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recommendations! Published in 2020 at "Tetrahedron Letters"

DOI: 10.1016/j.tetlet.2019.151453

Abstract: Abstract An unexpected Lewis acid-catalyzed [3+2] cycloaddition reaction of 1-substituted-3-arylvinylindoles was revealed when we studied the chemistry of donor-acceptor cyclobutanes and 1-substituted-3-arylvinylindoles. This method provides a simple, efficient route to synthesis of highly functionalized fused… read more here.

Keywords: lewis acid; fused cyclopenta; substituted arylvinylindoles; functionalized fused ... See more keywords
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Pd-Catalyzed intramolecular C–H addition to the cyano-group: construction of functionalized 2,3-fused thiophene scaffolds

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recommendations! Published in 2018 at "Organic chemistry frontiers"

DOI: 10.1039/c7qo01000a

Abstract: An efficient synthesis of 2,3-fused thiophenes was demonstrated through a Pd-catalyzed intramolecular C–H addition of thiophenes bearing cyanohydrin components at the C(3) positions to nitriles. A diversity of functionalized fused thiophenes with saturated six-, seven-… read more here.

Keywords: addition cyano; intramolecular addition; cyano group; functionalized fused ... See more keywords

Dipolarophile-Controlled Regioselective 1,3-Dipolar Cycloaddition: A Switchable Divergent Access to Functionalized N-Fused Pyrrolidinyl Spirooxindoles

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recommendations! Published in 2023 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms24043771

Abstract: N-fused pyrrolidinyl spirooxindole belongs to a class of privileged heterocyclic scaffolds and is prevalent in natural alkaloids and synthetic pharmaceutical molecules. To realize the switchable synthesis of divergent N-fused pyrrolidinyl spirooxindoles for further biological activity… read more here.

Keywords: dipolar cycloaddition; dipolarophile controlled; pyrrolidinyl spirooxindoles; functionalized fused ... See more keywords