Synthesis of Functionalized δ‐Hydroxy‐β‐keto Esters and Evaluation of Their Anti‐inflammatory Properties
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DOI: 10.1002/cbic.202200073
Abstract: δ‐Hydroxy‐β‐keto esters and δ,β‐dihydroxy esters are characteristic structural motifs of statin‐type natural products and drug candidates. Here, we describe the synthesis of functionalized δ‐hydroxy‐β‐keto esters in good yields and excellent enantioselectivities using Chan's diene and… read more here.
Keywords: synthesis functionalized; functionalized hydroxy; hydroxy keto; keto esters ... See more keywords