Articles with "functionalized liposomes" as a keyword



LinTT1 peptide-functionalized liposomes for targeted breast cancer therapy.

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Published in 2021 at "International journal of pharmaceutics"

DOI: 10.1016/j.ijpharm.2021.120346

Abstract: Breast cancer, with around 2 million new cases in 2019, is the second most common cancer worldwide and the second leading cause of cancer death among females. The aim of this work is to prepare… read more here.

Keywords: breast cancer; peptide functionalized; lintt1 peptide; functionalized liposomes ... See more keywords

Synthesis and Characterization of Transferrin and Cell-Penetrating Peptide-Functionalized Liposomal Nanoparticles to Deliver Plasmid ApoE2 In Vitro and In Vivo in Mice.

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Published in 2024 at "Molecular pharmaceutics"

DOI: 10.1021/acs.molpharmaceut.4c00870

Abstract: Alzheimer's disease (AD) is a prevalent neurodegenerative condition characterized by the aggregation of amyloid-β plaques and neurofibrillary tangles in the brain, leading to synaptic dysfunction and neuronal degeneration. Recently, new treatment approaches involving drugs such… read more here.

Keywords: treatment; brain; functionalized liposomes; dual functionalized ... See more keywords

Functionalized liposomes for intranasal levodopa delivery to the brain

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Published in 2025 at "Drug Development and Industrial Pharmacy"

DOI: 10.1080/03639045.2025.2509273

Abstract: Abstract Objective The study evaluated functionalized liposomes as potential carriers for intranasal delivery of levodopa. Methods Lipid film hydration method was used to obtain conventional and functionalized liposomes with polyethylene glycol or maleimide-PEG. The liposome… read more here.

Keywords: delivery; levodopa delivery; intranasal levodopa; delivery brain ... See more keywords
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Tat-Functionalized Liposomes for the Treatment of Meningitis: An in vitro Study [Corrigendum]

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Published in 2020 at "International Journal of Nanomedicine"

DOI: 10.2147/ijn.s292362

Abstract: [This corrects the article DOI: 10.2147/IJN.S130125.]. read more here.

Keywords: tat functionalized; treatment meningitis; vitro study; liposomes treatment ... See more keywords

Antitumor effects of docetaxel in truncated basic fibroblast growth factor-functionalized liposomes delivered by d-α-tocopheryl polyethylene glycol 2000 succinate.

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Published in 2020 at "Current pharmaceutical design"

DOI: 10.2174/1381612826666200423093357

Abstract: BACKGROUND PEGylation of stealth liposomes elevates their stability and prolongs plasma halflife. Stealth liposomes modified with targeting ligands are expected to be ideal drug delivery carriers. OBJECTIVE To encapsulate docetaxel in tbFGF (truncated basic fibroblast… read more here.

Keywords: tbfgf; fibroblast growth; truncated basic; functionalized liposomes ... See more keywords

Transferrin-Functionalized Liposomes for the Delivery of Gallic Acid: A Therapeutic Approach for Alzheimer’s Disease

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Published in 2022 at "Pharmaceutics"

DOI: 10.3390/pharmaceutics14102163

Abstract: Senile plaques composed of amyloid β (Aβ) fibrils are considered the leading cause of Alzheimer’s disease (AD). Molecules with the ability to inhibit Aβ aggregation and/or promote Aβ clearance are thus a promising approach for… read more here.

Keywords: gallic acid; alzheimer disease; functionalized liposomes; delivery ... See more keywords

Dual Functionalized Liposomes for Selective Delivery of Poorly Soluble Drugs to Inflamed Brain Regions

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Published in 2022 at "Pharmaceutics"

DOI: 10.3390/pharmaceutics14112402

Abstract: Dual functionalized liposomes were developed to cross the blood–brain barrier (BBB) and to release their cargo in a pathological matrix metalloproteinase (MMP)-rich microenvironment. Liposomes were surface-functionalized with a modified peptide deriving from the receptor-binding domain… read more here.

Keywords: mmp sensitive; brain; functionalized liposomes; dual functionalized ... See more keywords

Aptamer-Functionalized Liposomes as a Potential Treatment for Basal Cell Carcinoma

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Published in 2019 at "Polymers"

DOI: 10.3390/polym11091515

Abstract: More than one out of every three new cancers is a skin cancer, and the large majority are basal cell carcinomas (BCC). Targeted therapy targets the cancer’s specific genes, proteins, or tissue environment that contributes… read more here.

Keywords: cell carcinoma; basal cell; functionalized liposomes; cancer ... See more keywords