Granzyme B Functionalized Nanoparticles Targeting Membrane Hsp70-Positive Tumors for Multimodal Cancer Theranostics.
Sign Up to like & getrecommendations! Published in 2019 at "Small"
DOI: 10.1002/smll.201900205
Abstract: Functionalized superparamagnetic iron oxide nanoparticles (SPIONs) have emerged as potential clinical tools for cancer theranostics. Membrane-bound 70 kDa heat shock protein (mHsp70) is ubiquitously expressed on the cell membrane of various tumor types but not… read more here.
Keywords: granzyme functionalized; functionalized nanoparticles; membrane; cancer theranostics ... See more keywords
Enhancing Protein Crystal Nucleation Using In Situ Templating on Bioconjugate-Functionalized Nanoparticles and Machine Learning
Sign Up to like & getrecommendations! Published in 2023 at "ACS Applied Materials & Interfaces"
DOI: 10.1021/acsami.2c17208
Abstract: Although protein crystallization offers a promising alternative to chromatography for lower-cost protein purification, slow nucleation kinetics and high protein concentration requirements are major barriers for using crystallization as a viable strategy in downstream protein purification.… read more here.
Keywords: bioconjugate functionalized; nucleation; machine learning; crystallization ... See more keywords
Insight into Sonoluminescence Augmented by ZnO-Functionalized Nanoparticles
Sign Up to like & getrecommendations! Published in 2022 at "ACS Omega"
DOI: 10.1021/acsomega.1c05837
Abstract: Recent advances in optical imaging techniques rely on the use of nanosized contrast agents for in vitro and in vivo applications. We report on an imaging method based on the inertial cavitation of ultrasound-irradiated water… read more here.
Keywords: insight sonoluminescence; zno functionalized; sonoluminescence; augmented zno ... See more keywords
Immunoconjugates for cancer targeting: a review of antibody-drug conjugates and antibody-functionalized nanoparticles.
Sign Up to like & getrecommendations! Published in 2020 at "Current medicinal chemistry"
DOI: 10.2174/0929867327666200525161359
Abstract: Targeted therapy has been recently highlighted due to the reduction of side effects and improvement in overall efficacy and survival to different types of cancers. Considering the approval of many monoclonal antibodies in the last… read more here.
Keywords: antibody functionalized; antibody; drug; review antibody ... See more keywords
Lectins as Ligands for Directing Nanostructured Systems.
Sign Up to like & getrecommendations! Published in 2018 at "Current drug delivery"
DOI: 10.2174/1567201815666180108101246
Abstract: Lectins are proteins / glycoproteins of non-immunological origin found ubiquitously in all organisms. Research investigations show that many types of diseased tissues often display glycans that vary from their normal counterparts. Therefore, lectins that can… read more here.
Keywords: lectins ligands; lectin functionalized; ligands directing; nanostructured systems ... See more keywords
Functionalized Nanoparticles in Prevention and Targeted Therapy of Viral Diseases With Neurotropism Properties, Special Insight on COVID-19
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2021.767104
Abstract: Neurotropic viruses have neural-invasive and neurovirulent properties to damage the central nervous system (CNS), leading to humans’ fatal symptoms. Neurotropic viruses comprise a lot of viruses, such as Zika virus (ZIKV), herpes simplex virus (HSV),… read more here.
Keywords: nanoparticles prevention; targeted therapy; therapy viral; prevention targeted ... See more keywords
Patterning of Polymer-Functionalized Nanoparticles with Varied Surface Mobilities of Polymers
Sign Up to like & getrecommendations! Published in 2023 at "Materials"
DOI: 10.3390/ma16031254
Abstract: The polymers can be either dynamically tethered to or permanently grafted to the nanoparticle to produce polymer-functionalized nanoparticles. The surface mobility of polymer ligands with one end anchored to the nanoparticle can affect the surface… read more here.
Keywords: polymer; polymer functionalized; surface; patterning polymer ... See more keywords
Antioxidant Functionalized Nanoparticles: A Combat against Oxidative Stress
Sign Up to like & getrecommendations! Published in 2020 at "Nanomaterials"
DOI: 10.3390/nano10071334
Abstract: Numerous abiotic stresses trigger the overproduction of reactive oxygen species (ROS) that are highly toxic and reactive. These ROS are known to cause damage to carbohydrates, DNA, lipids and proteins, and build the oxidative stress… read more here.
Keywords: combat oxidative; nanoparticles combat; antioxidant functionalized; functionalized nanoparticles ... See more keywords
Unique Properties of Surface-Functionalized Nanoparticles for Bio-Application: Functionalization Mechanisms and Importance in Application
Sign Up to like & getrecommendations! Published in 2022 at "Nanomaterials"
DOI: 10.3390/nano12081333
Abstract: This review tries to summarize the purpose of steadily developing surface-functionalized nanoparticles for various bio-applications and represents a fascinating and rapidly growing field of research. Due to their unique properties—such as novel optical, biodegradable, low-toxicity,… read more here.
Keywords: application; unique properties; functionalization; functionalized nanoparticles ... See more keywords
Recent Advances in Functionalized Nanoparticles in Cancer Theranostics
Sign Up to like & getrecommendations! Published in 2022 at "Nanomaterials"
DOI: 10.3390/nano12162826
Abstract: Cancer theranostics is the combination of diagnosis and therapeutic approaches for cancer, which is essential in personalized cancer treatment. The aims of the theranostics application of nanoparticles in cancer detection and therapy are to reduce… read more here.
Keywords: nanoparticles cancer; functionalized nanoparticles; cancer treatment; cancer ... See more keywords
Polyphenols Epigallocatechin Gallate and Resveratrol, and Polyphenol-Functionalized Nanoparticles Prevent Enterovirus Infection through Clustering and Stabilization of the Viruses
Sign Up to like & getrecommendations! Published in 2021 at "Pharmaceutics"
DOI: 10.3390/pharmaceutics13081182
Abstract: To efficiently lower virus infectivity and combat virus epidemics or pandemics, it is important to discover broadly acting antivirals. Here, we investigated two naturally occurring polyphenols, Epigallocatechin gallate (EGCG) and Resveratrol (RES), and polyphenol-functionalized nanoparticles… read more here.
Keywords: functionalized nanoparticles; epigallocatechin gallate; polyphenols epigallocatechin; polyphenol functionalized ... See more keywords