Tyrosine-Specific Modification via a Dearomatization-Rearomatization Strategy: Access to Azobenzene Functionalized Peptides.
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DOI: 10.1021/acs.orglett.1c01013
Abstract: Azobenzene functionalized peptides are of great importance in photoresponsive biosystems and photopharmacology. Herein, we report an efficient approach to prepare azobenzene functionalized peptides through late-stage modification of tyrosine-containing peptides using a dearomatization-rearomatization strategy. This approach… read more here.
Keywords: azobenzene functionalized; functionalized peptides; rearomatization strategy; dearomatization rearomatization ... See more keywords