On-DNA Synthesis of Functionalized 4H-Pyran Scaffolds for Focused DNA-Encoded Chemical Libraries.
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DOI: 10.1021/acs.orglett.2c02714
Abstract: The functionalized 4H-pyran scaffold has aroused synthetic attention because it is widely found in many interesting pharmacologically relevant compounds. We here disclose its incorporation into DNA-encoded chemical libraries, combining this scaffold with the merits of… read more here.
Keywords: encoded chemical; dna; chemical libraries; dna encoded ... See more keywords