Synthesis of Functionalized Quinolines from 4-(o-Nitroaryl)-Substituted 3-Acyl-4,5-Dihydrofurans: Reductive Cyclization and C=C Bond Cleavage
Sign Up to like & getrecommendations! Published in 2017 at "European Journal of Organic Chemistry"
DOI: 10.1002/ejoc.201700256
Abstract: A new synthetic approach to functionalized quinolines was developed based on the application of Zn–AcOH system as a simple and efficient reductive agent towards 4-(o-nitroaryl)-3-acyl-substituted 4,5-dihydrofurans. Reduction of 3-carbonyl-substituted dihydrofurans is accomplished by C=C double-bond… read more here.
Keywords: synthesis functionalized; functionalized quinolines; cyclization; bond cleavage ... See more keywords
Metal-Free Synthesis of Functionalized Quinolines from 2-Styrylanilines and 2-Methylbenzothiazoles/2-Methylquinolines
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DOI: 10.1021/acsomega.2c07736
Abstract: A facile functionalization of C(sp3)–H bonds and tandem cyclization strategy to synthesize quinoline derivatives from 2-methylbenzothiazoles or 2-methylquinolines and 2-styrylanilines has been developed. This work avoids the requirement for transition metals, offering a mild approach… read more here.
Keywords: quinolines styrylanilines; synthesis functionalized; metal free; methylbenzothiazoles methylquinolines ... See more keywords
Hydride transfer-initiated synthesis of 3-functionalized quinolines by deconstruction of isoquinoline derivatives.
Sign Up to like & getrecommendations! Published in 2022 at "Chemical communications"
DOI: 10.1039/d2cc00127f
Abstract: Under transition metal catalyst-free conditions, we herein present a hydride transfer-initiated construction of novel 3-(2-aminomethyl)aryl quinolines from N-isoquinolinium salts and 2-aminobenzaldehydes, proceeding with the merits of operational simplicity, high step and atom efficiency, good substrate… read more here.
Keywords: synthesis functionalized; initiated synthesis; functionalized quinolines; transfer initiated ... See more keywords