Systematic acute and subchronic toxicity evaluation of polysaccharide-protein complex-functionalized selenium nanoparticles with anticancer potency.
Sign Up to like & getrecommendations! Published in 2019 at "Biomaterials science"
DOI: 10.1039/c9bm01104h
Abstract: Functionalized selenium nanoparticles (SeNPs) have demonstrated potential for applications in cancer chemotherapy, radio-sensitization, nephroprotection and drug delivery. However, their clinical application requires further systemic safety evaluation. Therefore, in this study, we examine the systematic acute… read more here.
Keywords: acute; functionalized selenium; toxicity; subchronic toxicity ... See more keywords
Polydopamine-functionalized selenium nanoparticles as an efficient photoresponsive antibacterial platform
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DOI: 10.1039/d2ra07737j
Abstract: A photoresponsive therapeutic antibacterial platform was designed and constructed using polydopamine-functionalized selenium nanoparticles as a carrier loaded with indocyanine green (Se@PDA-ICG). The therapeutic platform was confirmed by characterization and the antibacterial activity of Se@PDA-ICG against… read more here.
Keywords: functionalized selenium; platform; polydopamine functionalized; antibacterial platform ... See more keywords
Enhancing Radiotherapy Sensitivity in Prostate Cancer with Lentinan-Functionalized Selenium Nanoparticles: Mechanistic Insights and Therapeutic Potential
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DOI: 10.3390/pharmaceutics16091230
Abstract: Radiation therapy is a cornerstone of prostate cancer (PCa) treatment. However, its limited tumor sensitivity and severe side effects restrict its clinical utility. Lentinan-functionalized selenium nanoparticles (LET-SeNPs) have shown promise in enhancing radiotherapy sensitivity and… read more here.
Keywords: functionalized selenium; prostate cancer; sensitivity; let senps ... See more keywords
Lentinan-functionalized Selenium Nanoparticles target Tumor Cell Mitochondria via TLR4/TRAF3/MFN1 pathway
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DOI: 10.7150/thno.46467
Abstract: Rationale: Malignant ascites caused by cancer cells results in poor prognosis and short average survival time. No effective treatment is currently available for malignant ascites. In this study, the effects of lentinan (LNT)-functionalized selenium nanoparticles… read more here.
Keywords: malignant ascites; functionalized selenium; pathway; selene ... See more keywords