Anatomically and Functionally Distinct Lung Mesenchymal Populations Marked by Lgr5 and Lgr6
Sign Up to like & getrecommendations! Published in 2017 at "Cell"
DOI: 10.1016/j.cell.2017.07.028
Abstract: Summary The diversity of mesenchymal cell types in the lung that influence epithelial homeostasis and regeneration is poorly defined. We used genetic lineage tracing, single-cell RNA sequencing, and organoid culture approaches to show that Lgr5… read more here.
Keywords: anatomically functionally; functionally distinct; lgr5 lgr6; lgr6 ... See more keywords
Extracellular Spike Waveform Dissociates Four Functionally Distinct Cell Classes in Primate Cortex
Sign Up to like & getrecommendations! Published in 2019 at "Current Biology"
DOI: 10.1016/j.cub.2019.07.051
Abstract: Understanding the function of different neuronal cell types is key to understanding brain function. However, cell-type diversity is typically overlooked in electrophysiological studies in awake behaving animals. Here, we show that four functionally distinct cell… read more here.
Keywords: spike waveform; distinct cell; functionally distinct; cell classes ... See more keywords
Functionally-distinct pyramidal cell subpopulations during gamma oscillations in mouse hippocampal area CA3
Sign Up to like & getrecommendations! Published in 2022 at "Progress in Neurobiology"
DOI: 10.1016/j.pneurobio.2021.102213
Abstract: Gamma oscillations (γ-oscillations) in hippocampal area CA3 are essential for memory function. Particularly, CA3 is involved in the memory related process pattern completion, which is linked with the γ-oscillations in human hippocampus. Recent studies suggest… read more here.
Keywords: functionally distinct; hippocampal area; ca3; gamma oscillations ... See more keywords
The Medial and Lateral Lemnisci: Anatomically Adjoined But Functionally Distinct Fiber Tracts.
Sign Up to like & getrecommendations! Published in 2017 at "World neurosurgery"
DOI: 10.1016/j.wneu.2016.11.095
Abstract: OBJECTIVE The dense and complex distribution of neural structures in the brainstem makes it challenging to understand their real configuration. We used the fiber microdissection technique to show the course of the medial and lateral… read more here.
Keywords: lateral lemnisci; functionally distinct; fiber microdissection; brainstem ... See more keywords
Functionally distinct and selectively phosphorylated GPCR subpopulations co-exist in a single cell
Sign Up to like & getrecommendations! Published in 2018 at "Nature Communications"
DOI: 10.1038/s41467-018-03459-7
Abstract: G protein-coupled receptors (GPCRs) transduce pleiotropic intracellular signals in a broad range of physiological responses and disease states. Activated GPCRs can undergo agonist-induced phosphorylation by G protein receptor kinases (GRKs) and second messenger-dependent protein kinases… read more here.
Keywords: single cell; exist single; protein; functionally distinct ... See more keywords
Cellular census of human fibrosis defines functionally distinct stromal cell types and states
Sign Up to like & getrecommendations! Published in 2020 at "Nature Communications"
DOI: 10.1038/s41467-020-16264-y
Abstract: Fibrotic disorders are some of the most devastating and poorly treated conditions in developed nations, yet effective therapeutics are not identified for many of them. A major barrier for the identification of targets and successful… read more here.
Keywords: human fibrosis; distinct stromal; stromal cell; functionally distinct ... See more keywords
Propofol disrupts alpha dynamics in functionally distinct thalamocortical networks during loss of consciousness
Sign Up to like & getrecommendations! Published in 2023 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2207831120
Abstract: Significance Although anesthetic drugs are known to lower arousal, it is unclear how anesthesia impacts perceptual and cognitive processing. Diminished arousal has been associated with prominent brain oscillations such as the slow wave, but functional… read more here.
Keywords: functionally distinct; disrupts alpha; distinct thalamocortical; alpha dynamics ... See more keywords
A spatially and functionally distinct pool of TORC1 defines signaling endosomes in yeast
Sign Up to like & getrecommendations! Published in 2019 at "Autophagy"
DOI: 10.1080/15548627.2019.1580107
Abstract: ABSTRACT The evolutionarily conserved target of rapamycin complex 1 (TORC1) regulates cell growth in a homeostatic manner by tuning anabolic and catabolic processes in response to nutritional and hormonal cues. Interestingly, rather than being localized… read more here.
Keywords: torc1; distinct pool; spatially functionally; functionally distinct ... See more keywords
Two functionally distinct subsets of IL‐17 producing γδ T cells
Sign Up to like & getrecommendations! Published in 2020 at "Immunological Reviews"
DOI: 10.1111/imr.12905
Abstract: The γδ T cells play an important role in both mice and humans as a source of the cytokine IL‐17, which is key for immune resistance to certain pathogens. In mice, most of these IL‐17… read more here.
Keywords: distinct subsets; producing cells; subsets producing; functionally distinct ... See more keywords
A global assessment of the ‘island rule’ in bats based on functionally distinct measures of body size
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Biogeography"
DOI: 10.1111/jbi.14624
Abstract: The ‘island rule’ postulates that on islands large continental animals become smaller, and small continental animals become larger. Its generality has been supported by some studies but contested by others. Bats are cosmopolitan and speciose… read more here.
Keywords: island rule; functionally distinct; distinct measures; measures body ... See more keywords
Functionally Distinct Tendons From Elastin Haploinsufficient Mice Exhibit Mild Stiffening and Tendon-Specific Structural Alteration.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of biomechanical engineering"
DOI: 10.1115/1.4037932
Abstract: Elastic fibers are present in low quantities in tendon, where they are located both within fascicles near tenocytes and more broadly in the interfascicular matrix (IFM). While elastic fibers have long been known to be… read more here.
Keywords: elastic fibers; distinct tendons; functionally distinct; tendon ... See more keywords