Functionally impaired isoforms regulate TMPRSS6 proteolytic activity
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DOI: 10.1371/journal.pone.0273825
Abstract: TMPRSS6 is a type II transmembrane serine protease involved in iron homeostasis expressed as 4 isoforms in humans. TMPRSS6 isoform 2 downregulates hepcidin production by cleaving hemojuvelin and other surface proteins of hepatocytes. The functions… read more here.
Keywords: tmprss6 isoforms; impaired isoforms; proteolytic activity; functionally impaired ... See more keywords
Network analysis of anxiety and depression in the functionally impaired elderly
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Public Health"
DOI: 10.3389/fpubh.2022.1067646
Abstract: Background Evidence from previous studies has confirmed that functionally impaired elderly individuals are susceptible to comorbid anxiety and depression. Network theory holds that the comorbidity emerges from interactions between anxiety and depression symptoms. This study… read more here.
Keywords: impaired elderly; network; anxiety depression; anxiety ... See more keywords