Articles with "functionally important" as a keyword



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Residue coevolution reveals functionally important intramolecular interactions in formamidopyrimidine-DNA glycosylase.

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Published in 2018 at "DNA repair"

DOI: 10.1016/j.dnarep.2018.07.004

Abstract: In protein evolution, functionally important intramolecular interactions, such as polar bridges or hydrophobic interfaces, tend to be conserved. We have analyzed coevolution of physicochemical properties in pairs of amino acid residues in the formamidopyrimidine-DNA glycosylase… read more here.

Keywords: coevolution; important intramolecular; dna glycosylase; functionally important ... See more keywords
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Production and biophysical characterization of a mini-membrane protein, Ost4V23D: A functionally important mutant of yeast oligosaccharyltransferase subunit Ost4p.

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Published in 2017 at "Protein expression and purification"

DOI: 10.1016/j.pep.2017.07.009

Abstract: N-linked glycosylation of proteins is an essential and highly conserved co- and post-translational protein modification reaction that occurs in all eukaryotes. Oligosaccharyltransferase (OST), a multi-subunit membrane-associated enzyme complex, carries out this reaction. In the central… read more here.

Keywords: protein; biophysical characterization; functionally important; subunit ... See more keywords
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Surprising Rigidity of Functionally Important Water Molecules Buried in the Lipid Headgroup Region.

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Published in 2022 at "Journal of the American Chemical Society"

DOI: 10.1021/jacs.2c02145

Abstract: Understanding water dynamics and structure is an important topic in biological systems. It is generally held in the literature that the interfacial water of hydrated phospholipids is highly mobile, in fast exchange with the bulk… read more here.

Keywords: interfacial water; water; bulk water; water molecules ... See more keywords
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Loss of functionally important and regionally endemic species from streams forced into intermittency by global warming

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Published in 2023 at "Global Change Biology"

DOI: 10.1111/gcb.16650

Abstract: Climate change is altering hydrological cycles globally, and in Mediterranean (med‐) climate regions it is causing the drying of river flow regimes, including the loss of perennial flows. Water regime exerts a strong influence over… read more here.

Keywords: important regionally; intermittency; stream; loss ... See more keywords
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Youth E-Cigarette Use and Functionally Important Respiratory Symptoms: The Population Assessment of Tobacco and Health (PATH) Study Waves 3 and 4

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Published in 2022 at "International Journal of Environmental Research and Public Health"

DOI: 10.3390/ijerph192215324

Abstract: Respiratory effects of e-cigarette use among youth are not fully understood. This study investigated the longitudinal association between e-cigarette use and a validated index of functionally important respiratory symptoms among US youth. Data from Waves… read more here.

Keywords: cigarette use; functionally important; use; important respiratory ... See more keywords