Biological Functions of Autophagy Genes: A Disease Perspective
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DOI: 10.1016/j.cell.2018.09.048
Abstract: The lysosomal degradation pathway of autophagy plays a fundamental role in cellular, tissue, and organismal homeostasis and is mediated by evolutionarily conserved autophagy-related (ATG) genes. Definitive etiological links exist between mutations in genes that control… read more here.
Keywords: genes disease; autophagy genes; biological functions; functions autophagy ... See more keywords
The functions of autophagy at the tumour‐immune interface
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DOI: 10.1111/jcmm.16331
Abstract: Autophagy is frequently induced in the hypoxic tumour microenvironment. Accumulating evidence reveals important functions of autophagy at the tumour‐immune interface. Herein, we propose an update on the roles of autophagy in modulating tumour immunity. Autophagy… read more here.
Keywords: immune interface; functions autophagy; autophagy tumour; tumour immune ... See more keywords
Diverse Functions of Autophagy in Liver Physiology and Liver Diseases
Sign Up to like & getrecommendations! Published in 2019 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms20020300
Abstract: Autophagy is a catabolic process by which eukaryotic cells eliminate cytosolic materials through vacuole-mediated sequestration and subsequent delivery to lysosomes for degradation, thus maintaining cellular homeostasis and the integrity of organelles. Autophagy has emerged as… read more here.
Keywords: liver diseases; diverse functions; functions autophagy; physiology ... See more keywords