Tanshinone functions as a coenzyme that confers gain of function of NQO1 to suppress ferroptosis
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DOI: 10.26508/lsa.202201667
Abstract: NQO1 catalyzes the reduction of tanshinones to detoxify lipid peroxyl radicals and inhibit ferroptosis both in vitro and in vivo, providing a molecular mechanism for the therapeutic effects of tanshinones, such as cardiac protection. Ferroptosis… read more here.
Keywords: functions coenzyme; tanshinone; gain function; tanshinone functions ... See more keywords