EVI1 drives leukemogenesis through aberrant ERG activation.
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DOI: 10.1182/blood.2022016592
Abstract: Chromosomal rearrangements involving the MDS1 and EVI1 complex locus (MECOM) on chromosome 3q26 define an aggressive subtype of acute myeloid leukemia (AML) that is associated with chemotherapy resistance and dismal prognosis. Established treatment regimens commonly… read more here.
Keywords: erg; aml; functions evi1; evi1 ... See more keywords