The functions of EZH2 in immune cells: Principles for novel immunotherapies
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Leukocyte Biology"
DOI: 10.1002/jlb.1ru0520-311r
Abstract: Enhancer of zeste homolog 2 (EZH2) is aberrantly expressed or mutated in multiple types of cancer cells and plays an oncogenic role in tumorigenesis and development in most cancers. Results from pilot clinical studies have… read more here.
Keywords: roles ezh2; cancer cells; functions ezh2; cancer ... See more keywords
Focus on the classical and non-classical functions of EZH2: Guide the development of inhibitors and degraders.
Sign Up to like & getrecommendations! Published in 2022 at "Pharmacological research"
DOI: 10.1016/j.phrs.2022.106159
Abstract: Enhancer of zeste homologue 2 (EZH2, also known as KMT6A) is found to be a member of the histone lysine methyltransferase family. An increasing number of studies have shown that in addition to methylating histones,… read more here.
Keywords: classical functions; focus classical; classical non; functions ezh2 ... See more keywords