Physiological functions of FBW7 in cancer and metabolism.
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DOI: 10.1016/j.cellsig.2018.02.009
Abstract: FBW7 is one of the most well characterized F-box proteins that serve as substrate recognition subunits of SCF (Skp1-Cullin 1-F-box proteins) E3 ubiquitin ligase complexes. SCFFBW7 plays key roles in regulating cell cycle progression, differentiation,… read more here.
Keywords: physiological functions; functions fbw7; cancer metabolism; fbw7 cancer ... See more keywords