Pro-tumorigenic functions of macrophages at the primary, invasive and metastatic tumor site
Sign Up to like & getrecommendations! Published in 2020 at "Cancer Immunology, Immunotherapy"
DOI: 10.1007/s00262-020-02616-6
Abstract: The tumor microenvironment (TME) not only facilitates cancer progression from the early formation to distant metastasis, but also it differs itself from time to time alongside the tumor evolution. Tumor-associated macrophages (TAMs), whether as pre-existing… read more here.
Keywords: pro tumorigenic; macrophages primary; functions macrophages; cancer ... See more keywords
Immunosuppressive Functions of M2 Macrophages Derived from iPSCs of Patients with ALS and Healthy Controls
Sign Up to like & getrecommendations! Published in 2020 at "iScience"
DOI: 10.1016/j.isci.2020.101192
Abstract: Summary Amyotrophic lateral sclerosis (ALS) is a disorder with immune alterations that augment disease severity. M2 macrophages benefit diabetic and nephrotic mice by suppressing the pro-inflammatory state. However, neither have M2 cells been investigated in… read more here.
Keywords: functions macrophages; immunosuppressive functions; macrophages derived; ipsc derived ... See more keywords
The Detrimental and Beneficial Functions of Macrophages After Cochlear Injury
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2021.631904
Abstract: Macrophages are the main intrinsic immune cells in the cochlea; they can be activated and play a complicated role after cochlear injury. Many studies have shown that the number of macrophages and their morphological characteristics… read more here.
Keywords: macrophages cochlear; detrimental beneficial; beneficial functions; functions macrophages ... See more keywords
Immune Regulatory Functions of Macrophages and Microglia in Central Nervous System Diseases
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24065925
Abstract: Macrophages can be characterized as a very multifunctional cell type with a spectrum of phenotypes and functions being observed spatially and temporally in various disease states. Ample studies have now demonstrated a possible causal link… read more here.
Keywords: immune regulatory; central nervous; microglia central; regulatory functions ... See more keywords
Tumor Cell-derived Extracellular Vesicles in Modulating Phenotypes and Immune Functions of Macrophages: Mechanisms and Therapeutic Applications
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Cancer"
DOI: 10.7150/jca.84632
Abstract: Tumor tissues consist of tumor cells and tumor stroma, which is structured by non-tumor cells and the extracellular matrix. Macrophages are the predominant immune cells in the tumor microenvironment (TME). Based on the intimate interaction… read more here.
Keywords: cell; extracellular vesicles; tumor cell; tumor ... See more keywords