Articles with "functions tigar" as a keyword



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Structure, regulation, and biological functions of TIGAR and its role in diseases.

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Published in 2021 at "Acta pharmacologica Sinica"

DOI: 10.1038/s41401-020-00588-y

Abstract: TIGAR (TP53-induced glycolysis and apoptosis regulator) is the downstream target gene of p53, contains a functional sequence similar to 6-phosphofructose kinase/fructose-2, 6-bisphosphatase (PFKFB) bisphosphatase domain. TIGAR is mainly located in the cytoplasm; in response to… read more here.

Keywords: regulation biological; functions tigar; biological functions; tigar role ... See more keywords