Recombinant AfusinC, an anionic fungal CSαβ defensin from Aspergillus fumigatus, exhibits antimicrobial activity against gram-positive bacteria
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DOI: 10.1371/journal.pone.0205509
Abstract: Antimicrobial peptides (AMPs) are short and generally positively charged peptides found in a wide variety of organisms. CSαβ defensins are a group of AMPs. These defensins are composed of an α-helix and a β-sheet linked… read more here.
Keywords: fungal defensin; antimicrobial activity; afusinc; anionic fungal ... See more keywords
Molecular Modification of Kex2 P1’ Site Enhances Expression and Druggability of Fungal Defensin
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DOI: 10.3390/antibiotics12040786
Abstract: Pichia pastoris is the widely used expression system for producing recombinant secretory proteins. It is known that Kex2 protease plays a vital role in the process of protein secretion, in which the P1’ site affects… read more here.
Keywords: molecular modification; fungal defensin; druggability; site ... See more keywords