Core Steps to the Azaphilone Family of Fungal Natural Products
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DOI: 10.1002/cbic.202100240
Abstract: Azaphilones are a family of polyketide‐based fungal natural products that exhibit interesting and useful bioactivities. This minireview explores the literature on various characterised azaphilone biosynthetic pathways, which allows for a proposed consensus scheme for the… read more here.
Keywords: family fungal; natural products; fungal natural; core steps ... See more keywords
Anticancer fungal natural products: Mechanisms of action and biosynthesis.
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DOI: 10.1016/j.ejmech.2020.112502
Abstract: Many fungal metabolites show promising anticancer properties both in vitro and in animal models, and some synthetic analogs of those metabolites have progressed into clinical trials. However, currently, there are still no fungi-derived agents approved as… read more here.
Keywords: natural products; fungal natural; products mechanisms; anticancer ... See more keywords
Total Heterologous Biosynthesis of Fungal Natural Products in Aspergillus nidulans.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of natural products"
DOI: 10.1021/acs.jnatprod.2c00487
Abstract: Fungal natural products comprise a wide range of bioactive compounds including important drugs and agrochemicals. Intriguingly, bioinformatic analyses of fungal genomes have revealed that fungi have the potential to produce significantly more natural products than… read more here.
Keywords: total heterologous; biosynthesis; natural products; heterologous biosynthesis ... See more keywords