Spirocitromycetin, a Fungal Polyketide with an Antiosteoporotic Pharmacophore.
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DOI: 10.1021/acs.jnatprod.1c01060
Abstract: Spirocitromycetin, an antiosteoporotic polyketide bearing a unique spirocycle, was characterized from a human mucus sputum-derived Penicillium velutinum. Its structure and absolute configuration were elucidated spectrally, with its biosynthetic pathway likely mediated via polivione, a reported… read more here.
Keywords: fungal polyketide; pharmacophore; polyketide antiosteoporotic; antiosteoporotic pharmacophore ... See more keywords