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Published in 2019 at "Journal of medicinal chemistry"
DOI: 10.1021/acs.jmedchem.9b00826
Abstract: The molecular chaperone Hsp90, essential in all eukaryotes, plays a multifaceted role in promoting survival, virulence and drug resistance across diverse pathogenic fungal species. The chaperone is also critically important, however, to the pathogen's human…
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Keywords:
design synthesis;
fungal selective;
hsp90;
hsp90 inhibitors ... See more keywords