Genomics‐driven discovery of a novel self‐resistance mechanism in the echinocandin‐producing fungus Pezicula radicicola
Sign Up to like & getrecommendations! Published in 2018 at "Environmental Microbiology"
DOI: 10.1111/1462-2920.14089
Abstract: The echinocandins are antifungal lipopeptides targeting fungi via noncompetitive inhibition of the β-1,3-d-glucan synthase FKS1 subunit. A novel echinocandin resistance mechanism involving an auxiliary copy of FKS1 in echinocandin-producing fungus Pezicula radicicola NRRL 12192 was… read more here.
Keywords: producing fungus; echinocandin producing; fungus pezicula; resistance mechanism ... See more keywords