Identification of novel furo[2,3-d]pyrimidine based chalcones as potent anti-breast cancer agents: synthesis, in vitro and in vivo biological evaluation
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DOI: 10.1039/d2ra00889k
Abstract: Various substituted synthetic chalcones demonstrated potent anti-cancer activities. In the current study a series of novel furo[2,3-d]pyrimidine based chalcones were synthesized as potential anticancer agents. Among the different substituted derivatives, two of the halogen bearing… read more here.
Keywords: novel furo; based chalcones; potent anti; pyrimidine based ... See more keywords
Synthesis, Cytostatic and Antibacterial Evaluations of Novel 1, 2, 3-Triazolyl-tagged Pyrimidine and Furo[2, 3-d]pyrimidine Derivatives
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DOI: 10.5562/cca3165
Abstract: C-5 alkynylated and N-1 alkylated pyrimidine derivatives were synthesized by N-alkylation reaction of 5-iodouracil in the presence of NaH, as a base, followed by Pd-catalyzed Sonogashira cross-coupling reaction of N-alkyl-5-iodouracil derivatives (1 and 2) with… read more here.
Keywords: furo pyrimidine; pyrimidine furo; pyrimidine derivatives; pyrimidine ... See more keywords