The dynamics of urine sodium concentration after intra-venous furosemide in patients with acute heart failure
Sign Up to like & getrecommendations! Published in 2024 at "European Heart Journal"
DOI: 10.1093/eurheartj/ehae666.1181
Abstract: The urine sodium concentration measured at 2 hours after the administration of intravenous (IV) furosemide in patients with acute heart failure (AHF) is recommended as a marker to assess the responsiveness to IV furosemide. However,… read more here.
Keywords: heart; furosemide; sodium; sodium concentration ... See more keywords
Furosemide suppresses ileal and colonic contractility via interactions with GABA‐A receptor in mice
Sign Up to like & getrecommendations! Published in 2017 at "Clinical and Experimental Pharmacology and Physiology"
DOI: 10.1111/1440-1681.12824
Abstract: The loop diuretic furosemide has an action to inhibit Na+–K+–2Cl− co‐transporter at the thick ascending limb of Henle's loop resulting in diuresis. Furosemide also has the non‐diuretic effects by binding to GABA‐A receptor which may… read more here.
Keywords: furosemide; gaba receptor; contraction; receptor ... See more keywords
Furosemide depresses the presynaptic fiber volley and modifies frequency-dependent axonal excitability in rat hippocampus.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of neurophysiology"
DOI: 10.1152/jn.00704.2016
Abstract: The loop diuretic furosemide is known to have anticonvulsant effects, believed to be exerted through blockade of glial Na+-K+-2Cl- cotransport causing altered volume regulation in brain tissue. The possibility that direct effects of furosemide on… read more here.
Keywords: fiber volley; furosemide; axonal excitability; excitability ... See more keywords
The Effects of Sodium-Glucose Cotransporter-2 Inhibitors on Implantable Cardioverter Defibrillator Shocks in Heart Failure Patients Undergoing Diuretic Therapy
Sign Up to like & getrecommendations! Published in 2024 at "Medical Principles and Practice"
DOI: 10.1159/000542172
Abstract: Abstract Objective: Implantable cardioverter defibrillators (ICDs) are the standard treatment for patients with reduced left ventricular ejection fraction (LVEF ≤35%) to reduce the risk of sudden cardiac death. Loop diuretics can cause electrolyte imbalances, leading… read more here.
Keywords: icd shocks; implantable cardioverter; furosemide; ventricular arrhythmias ... See more keywords
Abstract 17177: Furosemide Promotes Myocardial Fibrosis in Swine Heart Failure
Sign Up to like & getrecommendations! Published in 2020 at "Circulation"
DOI: 10.1161/circ.142.suppl_3.17177
Abstract: Introduction: Although frequently used in heart failure (HF), long-term furosemide exacerbates HF in a swine model. This paradoxical phenomenon may reflect furosemide-induced alterations in signaling proteins of the extracellular matrix (ECM) to increase fibrosis. Examination… read more here.
Keywords: fibrosis; control; furosemide; heart failure ... See more keywords
Preparation and Characterization of Furosemide Solid Dispersion with Enhanced Solubility and Bioavailability
Sign Up to like & getrecommendations! Published in 2022 at "AAPS PharmSciTech"
DOI: 10.1208/s12249-022-02208-w
Abstract: Furosemide (FMD), as a potent circulating diuretic, is commonly used for the treatment of hypertension and edema arising from cardiac, renal, and hepatic failure. However, the low solubility of furosemide restricts its dissolution and bioavailability.… read more here.
Keywords: furosemide; solubility; pvp k30; solid dispersion ... See more keywords
Cumulative Doses Predict the Risk of Furosemide-Induced Electrolyte Abnormalities in Critically Ill Neonates
Sign Up to like & getrecommendations! Published in 2022 at "Therapeutics and Clinical Risk Management"
DOI: 10.2147/tcrm.s369737
Abstract: Background Furosemide has limited indications in the term neonates. Its use in preterm neonates is off-label. Considering the dearth of data, we carried out a retrospective study evaluating the furosemide use and its effects on… read more here.
Keywords: ill neonates; critically ill; cumulative doses; furosemide ... See more keywords
Different Effects on Fluid Distribution between Tolvaptan and Furosemide in a Liver Cirrhosis Patient with Chronic Kidney Disease
Sign Up to like & getrecommendations! Published in 2019 at "Internal Medicine"
DOI: 10.2169/internalmedicine.2174-18
Abstract: A 73-year-old man with liver cirrhosis and advanced chronic kidney disease was admitted to our hospital due to bilateral lower leg edema and appetite loss. Furosemide to treat fluid retention markedly decreased extracellular water compared… read more here.
Keywords: tolvaptan; chronic kidney; furosemide; different effects ... See more keywords
Comparative analysis of furosemide and torsemide efficacy in 24 hours of acute heart failure admission
Sign Up to like & getrecommendations! Published in 2025 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2025.1643077
Abstract: Background Intravenous (IV) furosemide and torsemide represent a cornerstone of guideline-directed medical therapy for acute heart failure (AHF). However, the evidence regarding the superiority of each agent remains controversial. Methods The prospective, open-label, comparative study… read more here.
Keywords: torsemide group; furosemide group; furosemide; group ... See more keywords
Furosemide Promotes Inflammatory Activation and Myocardial Fibrosis in Swine with Tachycardia-Induced Heart Failure
Sign Up to like & getrecommendations! Published in 2025 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms26136088
Abstract: Loop diuretics like furosemide are commonly used in heart failure (HF) treatment, but their effects on disease progression are still unclear. Furosemide treatment accelerates HF deterioration in a swine model, but the mechanism of acceleration… read more here.
Keywords: treatment; heart failure; furosemide; myocardial fibrosis ... See more keywords
Is furosemide a nephrotoxic for hospitalized patients?
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Renal Injury Prevention"
DOI: 10.34172/jrip.2023.32164
Abstract: Introduction: Acute kidney disease (AKI) is preventable in certain situations. Long-term and/or high dose furosemide may lead to acute kidney injury. Objectives: We aimed to find the risk of AKI among hospitalised patients who were… read more here.
Keywords: acute kidney; kidney; kidney injury; furosemide ... See more keywords