Protein profiling uncovers IGF-1R inhibition potential of 3-(2-furoyl)-indole scaffolds in hepatocellular carcinoma.
Sign Up to like & getrecommendations! Published in 2025 at "Future medicinal chemistry"
DOI: 10.1080/17568919.2025.2467616
Abstract: AIM This study investigates the anti-proliferative potential and possible molecular mechanisms of 3-(2-furoyl)-indole derivatives against HepG2. METHOD Identified hit compounds (4a, 4b, 4c) using MTT screening, were further investigated for their efficacy and mechanism of… read more here.
Keywords: furoyl indole; protein profiling; hepatocellular carcinoma; potential ... See more keywords