Organocatalytic Asymmetric (3+3) Cycloaddition of 4‐Hydroxycoumarins with α,β‐Unsaturated Aryl Esters
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DOI: 10.1002/cctc.202401925
Abstract: Chiral six‐membered O‐heterocycle‐fused coumarins belong to one of the most important chiral O‐heterocycles, which are found in many natural products and bioactive molecules. Therefore, developing catalytic asymmetric strategies for the construction of chiral six‐membered O‐heterocycle‐fused… read more here.
Keywords: heterocycle fused; six membered; fused coumarins; membered heterocycle ... See more keywords
Three-component synthesis of pyran-fused biscoumarins: an entry to pyridinone- and pyranone-fused coumarins
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DOI: 10.1039/d4ra01681e
Abstract: A base-mediated, three-component synthesis of symmetric and unsymmetric pyran-fused biscoumarins via the coupling of 4-hydroxycoumarin with 4-chloro-3-formylcoumarin in ethanol is reported. This methodology is further extended to the construction of various indole/coumarin-substituted symmetric pyran-fused biscoumarins.… read more here.
Keywords: component synthesis; pyran fused; three component; fused coumarins ... See more keywords