Articles with "fused enediynes" as a keyword



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Pathway Retrofitting Yields Insights into the Biosynthesis of Anthraquinone-Fused Enediynes.

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Published in 2021 at "Journal of the American Chemical Society"

DOI: 10.1021/jacs.1c03911

Abstract: Anthraquinone-fused enediynes (AQEs) are renowned for their distinctive molecular architecture, reactive enediyne warhead, and potent anticancer activity. Although the first members of AQEs, i.e., dynemicins, were discovered three decades ago, how their nitrogen-containing carbon skeleton… read more here.

Keywords: insights biosynthesis; anthraquinone fused; pathway retrofitting; fused enediynes ... See more keywords