Trk-fused gene (TFG) regulates pancreatic β cell mass and insulin secretory activity
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/s41598-017-13432-x
Abstract: The Trk-fused gene (TFG) is reportedly involved in the process of COPII-mediated vesicle transport and missense mutations in TFG cause several neurodegenerative diseases including hereditary motor and sensory neuropathy with proximal dominant involvement (HMSN-P). The… read more here.
Keywords: insulin; trk fused; tfg; fused gene ... See more keywords
A tropomyosin-receptor kinase-fused gene mutation associates with vacuolar myopathy
Sign Up to like & getrecommendations! Published in 2018 at "Neurology: Genetics"
DOI: 10.1212/nxg.0000000000000287
Abstract: A 44-year-old Caucasian man presented with a 7-year history of upper and lower limb muscle fasciculations and cramps, progressive asymmetric weakness, muscle atrophy, and length-dependent sensory loss. His parents (deceased), 3 older siblings, and 3… read more here.
Keywords: receptor kinase; muscle; weakness; tropomyosin receptor ... See more keywords