Synthesis and Antimicrobial Activity Evaluation of Imidazole‐Fused Imidazo[2,1‐b][1,3,4]thiadiazole Analogues
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DOI: 10.1002/cmdc.202100122
Abstract: Three series of new imidazole‐fused imidazo[2,1‐b][1,3,4]thiadiazole analogues (compounds 20 a–g, 21 a–g, and 22 a–g) have been synthesized, and their antibacterial and antifungal activities have been evaluated. All the target compounds showed strong antifungal activity and high selectivity… read more here.
Keywords: imidazo thiadiazole; fused imidazo; thiadiazole analogues; activity ... See more keywords
In-silico molecular modelling, MM/GBSA binding free energy and molecular dynamics simulation study of novel pyrido fused imidazo[4,5-c]quinolines as potential anti-tumor agents
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DOI: 10.3389/fchem.2022.991369
Abstract: With an alarming increase in the number of cancer patients and a variety of tumors, it is high time for intensive investigation on more efficient and potent anti-tumor agents. Though numerous agents have enriched the… read more here.
Keywords: fused imidazo; tumor agents; anti tumor; binding free ... See more keywords