Acid-promoted intra- and intermolecular [2+2] cycloaddition of indoles to aryl alkynes to access cyclobutene-fused indolines.
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DOI: 10.1039/d2cc02840a
Abstract: Herein, we have reported the first example of both intra- and intermolecular [2+2] cycloaddition of the electron-rich indoles and unactivated aryl alkynes promoted by the combination of Fe(NO3)3 and HNO3, which highlights efficient and selective… read more here.
Keywords: fused indolines; cyclobutene fused; intermolecular cycloaddition; aryl alkynes ... See more keywords