Facile synthesis of 1,2,3-triazole-fused indolo- and pyrrolo[1,4]diazepines, DNA-binding and evaluation of their anticancer activity.
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DOI: 10.1016/j.bioorg.2019.103306
Abstract: A facile synthetic strategy has been developed for the generation of structurally diverse N-fused heterocycles. The formation of fused 1,2,3-triazole indolo and pyrrolodiazepines proceeds through an initial Knoevenagel condensation followed by intramolecular azide-alkyne cycloaddition reaction… read more here.
Keywords: fused indolo; facile synthesis; triazole fused; synthesis triazole ... See more keywords